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People who suffer from erectile dysfunction or erectile dysfunction in men. Tadalafil, the active ingredient in
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, works by inhibiting the action of the phosphodiesterase type 5 (PDE5) enzyme. By inhibiting PDE5, Tadalafil allows cyclic guanosine monophosphate (cGMP) levels to increase in response to sexual stimulation. Elevated cGMP levels lead to the relaxation of smooth muscle cells in the penile arteries, resulting in increased blood flow to the erectile tissue and the ability to achieve and maintain an erection. It is necessary to take the medicine 30-40 minutes before engaging in sexual intercourse.
 

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